(3S*,4S*,E)-tert-Butyl 3,4-dibromo-5-oxocyclooct-1-enecarboxylate
نویسندگان
چکیده
The title compound, C(13)H(18)Br(2)O(3), was prepared by a bromination reaction of (1E,3Z)-methyl 5-oxocyclo-octa-1,3-diene-carboxyl-ate, which was obtained by an ep-oxy-dation reaction of tert-butyl cyclo-oct-1,3-diene-carboxyl-ate. The crystal structure confirms unequivocally the absolute configuration of both chiral centres to be S. In the crystal, C-H⋯O inter-actions link the mol-ecules into chains running along the c axis.
منابع مشابه
(3R,4S,5R)-Methyl 3,5-bis[(tert-butyldimethylsilyl)oxy]-4-methoxycyclohex-1-enecarboxylate
The title compound, C21H42O5Si2, was synthesized from (3R,4S,5R)-methyl 3,5-bis-[(tert-butyl-dimethyl-sil-yl)-oxy]-4-hy-droxy-cyclo-hex-1-ene-carboxyl-ate by an esterification reaction. The cyclo-hexene ring adopts a half-chair conformation. In the crystal, mol-ecules are linked via C-H⋯O hydrogen bonds, forming helical chains propagating along [010].
متن کامل(1S,3S,4S)-tert-Butyl N-[1-benzyl-3-hydroxy-5-phenyl-4-(picolinamido)pentyl]carbamate
The title compound, C(29)H(35)N(3)O(4), was obtained by the reaction of (2S,4S,5S)-tert-butyl N-(4-amino-1-benzyl-3-hydr-oxy-5-phenyl-pent-yl)carbamate and picolinic acid using oxalyl chloride as a chlorinating reagent to activate the carboxyl group. In the crystal structure there are two mol-ecules in the asymmetric unit, which are aligned edge-to-face. In one mol-ecule, the pyridyl ring forms...
متن کاملA Short and Efficient Synthesis of (2S,3S,4S)-tert-Butyl 3,4-Dihydroxy-2- (methoxymethyl)-5-oxopyrrolidine-1-carboxylate
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متن کاملA Short and Efficient Synthesis of (2S,3S,4S)-tert-Butyl 3,4-Dihydroxy-2- (methoxymethyl)-5-oxopyrrolidine-1-carboxylate Synthesis of the C33–C37 Fragment of Calyculin C
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متن کاملtert-Butyl 4-(4-chloroanilino)-6-methyl-2-oxocyclohex-3-enecarboxylate
In the title compound, C(18)H(22)ClNO(3), the dihedral angle between the benzene ring and the conjugated part of the enaminone ring is 55.19 (9)°. The ester substituent makes a dihedral angle of 81.0 (2)° with this latter moiety. The crystal structure features N-H⋯O and weak C-H⋯O inter-molecular inter-actions.
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